general_pathology:neoplasia:neoplasia_76
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In Marek's disease which of the following is important in the development of neoplasia?
”Explanation”
PBVD, 7th Ed. p520. Early in the infection of MDV, the virus causes cytolysis of lymphocytes. This helps any transformed cells which have had the Meq oncogene inserted to evade the immune system. Meq mimics c-Jun which is a transcription factor promoting cell growth and proliferation. https://www.mdpi.com/1999-4915/17/2/259
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