general_pathology:neoplasia:neoplasia_21
Choose the correct answer
Some lung adenocarcinomas become self sufficient in growth signals by chromosome translocations fusing which genes?
”Explanation”
A deletion on chromosome 5 fuses ELM4-ALK to make a chimeric protein which has tyrosine kinase activity.
NLM-ALK fusion happens in anaplastic large cell lymphoma.
ALK = Anaplastic lymphoma kinase
general_pathology/neoplasia/neoplasia_21.txt · Last modified: by achamings