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Which is true for hypersensitivity type 1 reactions?

The second antigen exposure induces cross linking of IgE on mast cells and is called the effector phase

The initial exposure to the antigen causes cross linking of IgE on mast cells and is called the effector phase

In response to chemotactic signals from mast cells, inflammatory cells are recruited in the late phase and neutrophils release major basic protein

Il-12 is important for the production of IgE in the Th2 inflammatory reaction inducing the type I hypersensitivity