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Choose the correct answer

Which is true about type-IV hypersensitivity reactions?

a) Are antibody mediated reactions. Damage is induced by IgM or IgG binding to host cells making them targets for phagocytes, by blocking cell receptors or stimulating receptors

b) Are cell mediated reactions where activated T cells release cytokines and recruit macrophages to cause tissue injury

c) Are immediate reactions induced by Th2 CD4 cells stimulating the production of IgE which primes mast cells to release vasoactive amines and ultimately inflammatory tissue damage

d) Are immune-complex mediate reactions in which immune complexes deposit in structures such as glomeruli and synovial membranes initiating local injury by leukocytes