Vet Pathology Wiki

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Perforins and granzymes have what effect on target cells?

Enter the target cell by endocytosis and activate caspases inducing apoptosis

Enter the target cell by endocytosis and cause calcium leakage in mitochondria and necrosis

Form pores in the plasma membrane resulting in loss of electrolytes and cell death

Enter the target cell by endocytosis and form pores in the mitochondria causing calcium leakage and cell death

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