Vet Pathology Wiki

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Pro-inflammatory cytokines induce glucose resistance in the liver by which mechanism?

The bind to serum insulin

They impair expression of the glucose transporter 4 (GLUT-4)

They bind to and inactivate the glucose transporter 4 (GLUT-4)

They bind to receptors IL-1R and TNFR on β cells to down regulate the production of insulin