Vet Pathology Wiki

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Which mutation most commonly affects prothrombin in humans?

A SNP within the 3' UTR results in increased expression of prothrombin

A SNP within the Prothrombin gene (F2) makes it more readily cleaved by factor X/V complexes

A deficiency of cystathione β-synthetase causes elevations in homocysteine resulting in cross linking of prothrombin with homocysteine metabolites

A SNP within the prothrombin (F2) gene makes it more resistant to plasminogen activator inhibitors