general_pathology:chronic:chronic_inflammation_33
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Which pro-macrophage signal homolog is produced by pathogens such as Leishmania?
”Explanation”
MIF actually promotes the survival of macrophages. Pathogens that want to live intracellularly will produce MIF to keep their host cells alive (e.g. Leishmania). It binds to CD74 - part of the MHC class II complex.
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