general_pathology:acute:acute_inflammation_70
Choose the correct answer
PAD4 has which of the following effects in the neutrophil?
”Explanation”
Citrullination of histones opens up the DNA. ROS and neutrophil elastase help cleave histone proteins. The DNA is then releases during cell lysis (suicide) or non-lytic - passed out in vesicles but neutrophil continues to live withouta nucleus for a while.
general_pathology/acute/acute_inflammation_70.txt · Last modified: by achamings