general_pathology:acute:acute_inflammation_59
Choose the correct answer
C3 convertase from the alternate complement pathway is comprised of which molecules?
”Explanation”
The C3 convertase of the classical and Lectin pathways is the same C4B2a
The C3 convertase of the alternate pathway is made of C3b and factor B (remember C3 is auto-cleaved by tissue damage or microbial products to start this pathway). Factor D cleaves Factor B which combines with C3b to form C3 convertase. Factor B is a soluble factor circulating in the blood and is produced by the liver and other tissues of the body (https://pmc.ncbi.nlm.nih.gov/articles/PMC11868072/).
general_pathology/acute/acute_inflammation_59.txt · Last modified: by achamings