general_pathology:neoplasia:neoplasia_60

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What is the mechanism of Avian Leukosis Virus tumorgenesis?

E7 protein inactivation of Rb

Insertion of viral DNA near Myc or TERT

Mimicry of host BCL- 2 activity by viral proteins

Disruption of host TP53 by viral DNA insertion

”Explanation”

From: https://journals.asm.org/doi/10.1128/jvi.01127-16