general_pathology:neoplasia:neoplasia

Choose the correct answer

Mutations to the gene CDKN2A which inactivate p16 in various neoplasias have which of the following effects?

Inhibition of Cyclin D/CDK4 complex

Inactivates Cyclin E/CDK2 complex

Dephosphorylation of Rb

Loss of inhibition of the Cyclin D/CDK4 complex