general_pathology:infectious:infectious_diseases

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Prior to spread to the nervous system, which cells are important for prion protein replication?

Follicular dendritic cells and B-cells

CD4 T-cells and macrophages

Neutrophils and macrophages

Plasma cells and NK cells

Replication in follicular dendritic cells and B-cells are important in lymphoid tissues (lymph nodes, spleen) PBVD 7th Ed p 293