Choose the correct answer
P. falciparum escapes the immune system by which mechanism?
Expressing different sequences for the VlsE surface protein via a plasmid with promoter and multiple encoding sequences
Through recombination of the outer membrane protein TprK
By recombination and expression of different OPA (opaque) proteins
Switching expression of antigenic variants of the PfEMP1 surface protein
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”Explanation”
Different recombination strategies:
Borellia - VlsE
Treponema (Syphilis) - TprK
Neisseria menigitidis and gonorrhoeae- OPA
Plasmodium falciparum - PfEMP1 - protein expressed on the surface of infected erythrocytes