general_pathology:immunology:innate_immunity

Choose the correct answer

Which of the following is true of NOD-like receptors?

They are present in the cytosol, they can identify products of cell damage and bacterial infection and induce the production of Il-1 via the NLRP-3 inflammasome and cleavage of Il-1 precursors by Caspase I

They are present in the plasma membrane, they can identify products of cell damage and induce the production of Il-1 via the NLRP-3 inflammasome and cleavage of Il-1 precursors by Caspase I

They are present in the plasma membrane of macrophages and dendritic cells and can identify fungal glycans

They are present in the cytosol and detect nucleic acids of viruses and activate the STING pathway

”Explanation”

From: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1122586/full