general_pathology:acute:acute_inflammation

Choose the correct answer

Activated platelets trigger netosis in neutrophils via which of the following pathways?

HMGB-1 binds to RAGE on the neutrophil

E-selectin binds to MAC1

L-selectin binds to TLR4 on the neutrophil

P-selectin binds to CCL5

α granules of platelets contain HMGB-1 (High Mobility Group Box 1). This is a soluble interaction between platelets and neutrophils. This is the Google AI summary of HMGB-1