{{ :general_pathology:neoplasia:neuroblastoma_myc.png |}} Multiple copies of nMyc might be inserted into the other autosome Other driver mutations to be aware of include: * Mutation of enhancer elements occur in prostate and ovarian carcinomas. * Dysregulated Wnt signalling occurs in some colon carcinomas. * Up regulation of RAS/MAPK signalling is common in many cancers (HSR: Homogenous staining region)