^ Fungus ^ Hyphae Width ^ Branching ^ Septae ^ Pigment ^ Parallel walls ^ Comments ^ | Candida sp. | 3-5μm | Can appear so | Yes | No | No - these are incompletely separated yeast | Can be challenging to differentiate from actual hyphae | | Aspergillus, Fusarium, Trichoderma sp. | 5-10 μm | Acute angle | Yes | No - hyaline (not pigmented)| Yes | Mucormycotina can sometimes have this morphology | | Mucormycotina | 6-50 μm | Right-angled | Pauciseptate | No - hyaline | Definitive separation from Aspergillus sp. requires further ID | | Phaeohyphomycosis (e.g. Exophiala, Exserohilium), and other pigmented moulds | | Yes | Yes | Melanin | May have yeast-like structures present as well | {{ :general_pathology:infectious:fungal_hyphae.png?direct |}} From: https://journals.asm.org/doi/10.1128/cmr.00053-10