Mannose Binding Lectin is a PAMP secreted by the liver and is an **acute phase protein** secreted in response to inflammatory cytokines such as Il-6. It has a similar structure to C1q hence why it activates the complement system via the mannose binding pathway. **It opsonizes a pathogen for phagocytosis**. {{ :general_pathology:acute:mannose_binding_lectin.png |}} From:https://pubmed.ncbi.nlm.nih.gov/14568388/