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--- general_pathology:neoplasia:neoplasia_25 [2026/02/24 22:30] – created achamings
+++ general_pathology:neoplasia:neoplasia_25 [2026/02/24 22:49] (current) – achamings
@@ Line 1: / Line 1: @@
 <quiz>
-<quiz-item choice question="Choose the correct answer" text="" options="a)|b)|c)|d)" answer="">
+<quiz-item choice question="Choose the correct answer" text="A common driver mutation in endometrial carcinoma causes a loss of function of which tumour suppressor gene?" options="GAP|PTEN|PI3K|MAPK" answer="PTEN">
 </quiz>
 <accordion>
 <accordion-item title=”Explanation”>
+RC 10th Ed. p287 - loss of function of PTEN means there is no negative feedback signal on PI3K (Phosphoinositide-3-Kinase)
+{{ :general_pathology:neoplasia:tyrosine-kinase-pathways.jpg |}}
 </accordion-item>
 </accordion>