general_pathology:neoplasia:neoplasia_14
Differences
This shows you the differences between two versions of the page.
| Both sides previous revisionPrevious revision | |||
| general_pathology:neoplasia:neoplasia_14 [2026/02/24 22:38] – achamings | general_pathology:neoplasia:neoplasia_14 [2026/02/24 23:33] (current) – achamings | ||
|---|---|---|---|
| Line 5: | Line 5: | ||
| < | < | ||
| Haploinsufficiency - when the loss of one normal allele of a tumour suppressor gene is sufficient to develop neoplasia even with a functionally normal allele. " | Haploinsufficiency - when the loss of one normal allele of a tumour suppressor gene is sufficient to develop neoplasia even with a functionally normal allele. " | ||
| + | |||
| + | Classic example is p53 - loss of function of 1 allele significantly increases the chance of neoplasia. | ||
| + | {{ : | ||
| + | |||
| </ | </ | ||
| </ | </ | ||
general_pathology/neoplasia/neoplasia_14.1771972727.txt.gz · Last modified: by achamings