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general_pathology:infectious:infectious_diseases_135

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general_pathology:infectious:infectious_diseases_135 [2026/03/06 05:17] – created achamingsgeneral_pathology:infectious:infectious_diseases_135 [2026/03/06 05:20] (current) achamings
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-<quiz-item choice question="Choose the correct answer" text="What mutation is particularly protective from P. vivax infection" options="Point mutations in globin genes - sickle cell disease|Globin deficiencies (α  and β thalassemias|Mutations in glucose-6-phosphate dehydrogenase in RBCs|Absence of Duffy surface blood group (DARC) band3 spectrin" answer="Absence of Duffy surface blood group (DARC) band3 spectrin">+<quiz-item choice question="Choose the correct answer" text="What mutation is particularly protective from P. vivax infection?" options="Point mutations in globin genes - sickle cell disease|Globin deficiencies (α  and β thalassemias|Mutations in glucose-6-phosphate dehydrogenase in RBCs|Absence of Duffy surface blood group (DARC) band3 spectrin" answer="Absence of Duffy surface blood group (DARC) band3 spectrin">
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 P.vivax specifically enters blood cells using Duffy surface blood group antigens and therefore the absence of these is protective - common in people from West Africa.  P.vivax specifically enters blood cells using Duffy surface blood group antigens and therefore the absence of these is protective - common in people from West Africa. 
  
-All these mutations are pathogenic in the homozygous form, but heterozygous individuals benefit from protection from P. falciparum +All these mutations are pathogenic in the homozygous form, but heterozygous individuals benefit from reduced susceptibility from P. falciparum 
 +{{ :general_pathology:infectious:plasmodium_resistance.png?direct |}}
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general_pathology/infectious/infectious_diseases_135.1772774267.txt.gz · Last modified: by achamings

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