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| general_pathology:environmental:toxic_and_environmental_diseases_74 [2026/05/25 03:00] – created achamings | general_pathology:environmental:toxic_and_environmental_diseases_74 [2026/05/25 03:01] (current) – achamings |
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| <quiz> | <quiz> |
| <quiz-item choice question="Choose the correct answer" text="" options="" answer=""> | <quiz-item choice question="Choose the correct answer" text="Which trace element is essential for the synthesis of melanin?" options="Iron|Manganese|Copper|Cobalt" answer="Copper"> |
| </quiz> | </quiz> |
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| <accordion-item title="Explanation"> | <accordion-item title="Explanation"> |
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| Melanin is biosynthesized from tyrosine in the melanosomes (organelles) of cells called melanocytes, and three enzymes, namely tyrosinase (TYR), tyrosinase‐related protein 1 (TYR1) and tyrosinase‐related protein 2 (TYR2), are involved in the biosynthetic process. Non‐expression of TYR causes albinism, whereas non‐expression of TYR1 leads to a brownish body/hair color. https://sj.jst.go.jp/news/202306/n0614-02k.html | Melanin is biosynthesized from tyrosine in the melanosomes (organelles) of cells called melanocytes, and three enzymes, namely tyrosinase (TYR), tyrosinase‐related protein 1 (TYR1) and tyrosinase‐related protein 2 (TYR2), are involved in the biosynthetic process. Non‐expression of TYR causes albinism, whereas non‐expression of TYR1 leads to a brownish body/hair color. https://sj.jst.go.jp/news/202306/n0614-02k.html |
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| Tyrosinase is a copper dependent enzyme (https://www.ncbi.nlm.nih.gov/books/NBK459156/) | Tyrosinase is a copper dependent enzyme (https://www.ncbi.nlm.nih.gov/books/NBK459156/) |
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| </accordion> | </accordion> |