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--- general_pathology:environmental:toxic_and_environmental_diseases_16 [2026/03/09 06:39] – created achamings
+++ general_pathology:environmental:toxic_and_environmental_diseases_16 [2026/03/09 06:46] (current) – achamings
@@ Line 1: / Line 1: @@
 <quiz>
-<quiz-item choice question="Choose the correct answer" text="1,25-dihydroxycholecalciferol encourages osteoblasts to do which of the following?" options="Express RANKL|Secrete osteocalcin|Secrete calcitonin|Secrete Cathepsin K" answer="Secrete osteocalcin">
+<quiz-item choice question="Choose the correct answer" text="1,25-dihydroxycholecalciferol encourages osteoblasts to do which of the following?" options="Secrete hydrochloric acid|Secrete osteocalcin|Secrete calcitonin|Secrete Cathepsin K" answer="Secrete osteocalcin">
 </quiz>
 <accordion>
 <accordion-item title=”Explanation”>
-Osteocalcin is involved in the deposition of calcium into osteoid matrix
+Osteocalcin is involved in the deposition of calcium into osteoid matrix. Vitamin D encourages the deposition of calcium.
+Osteoclasts are the cells that secrete HCl and Cathepsin when signaled to increase serum calcium (osteoblasts upregulate RANKL - determined by vitamin D levels and PTH interaction).
+Calcitonin is made by the thyroid C-cells to lower serum calcium
 {{ :general_pathology:environmental:bone_mineralization.png?direct |}}
 </accordion-item>
 </accordion>