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general_pathology:acute:acute_inflammation_59 [2026/02/28 09:23] – created achamingsgeneral_pathology:acute:acute_inflammation_59 [2026/03/02 23:49] (current) achamings
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 <accordion-item title=”Explanation”> <accordion-item title=”Explanation”>
 The C3 convertase of the classical and Lectin pathways is the same **C4B2a** The C3 convertase of the classical and Lectin pathways is the same **C4B2a**
-The C3 convertase of the alternate pathway is made of C3b and factor B (remember C3 is auto-cleaved by tissue damage or microbial products to start this pathway)+The C3 convertase of the alternate pathway is made of C3b and factor B (remember C3 is auto-cleaved by tissue damage or microbial products to start this pathway). Factor D cleaves Factor B which combines with C3b to form C3 convertase. Factor B is a soluble factor circulating in the blood and is produced by the liver and other tissues of the body (https://pmc.ncbi.nlm.nih.gov/articles/PMC11868072/). 
 {{ :general_pathology:acute:complement3.png |}} {{ :general_pathology:acute:complement3.png |}}
 +
 +{{ :general_pathology:acute:complement_factorb.png |}}
 +From: https://pmc.ncbi.nlm.nih.gov/articles/PMC11868072/
 +
 +
 +Also see: https://en.wikipedia.org/wiki/Complement_factor_B
 </accordion-item> </accordion-item>
 </accordion> </accordion>
general_pathology/acute/acute_inflammation_59.1772270580.txt.gz · Last modified: by achamings

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